Yes, American Holly is toxic to dogs!
Dogs accidentally consuming the American Holly plants can show the following clinical symptoms: Vomiting, Prolonged Depression, Incoordination, Hypersalivaton, Sleepiness Or Excitation, Dilated Pupils, Low Body Temperature, Low Blood Pressure, Coma, Seizure And Death (In Rare Cases).
American Holly consumption is also toxic to Cats and Horses.
Toxic Principles Of American Holly: saponins.
More Info About The American Holly Plant
Scientific Name: Ilex opaca
Family: Aquifoliaceae.
Also known as: English Holly, European Holly, Oregon Holly, Inkberry, Winterberry.
The answer is based on information found on The American Society for the Prevention of Cruelty to Animals (ASPCA) website.