Yes, American Mandrake is toxic to dogs!
Dogs accidentally consuming the American Mandrake plants can show the following clinical symptoms: Vomiting, Prolonged Depression, Incoordination, Hypersalivaton, Sleepiness Or Excitation, Dilated Pupils, Low Body Temperature, Low Blood Pressure, Coma, Seizure And Death (In Rare Cases).
American Mandrake consumption is also toxic to Cats and Horses.
Toxic Principles Of American Mandrake: Podophyllin.
More Info About The American Mandrake Plant
Scientific Name: Podophyllum peltatum
Family: Berberidaceae.
Also known as: Mayapple, Indian Apple Root, Umbrella Leaf, Wild Lemon, Hog Apple, Duck’s Foot, Raccoonberry.
The answer is based on information found on The American Society for the Prevention of Cruelty to Animals (ASPCA) website.